2021 Toyota Sienna maintenance schedule

The 2021 Sienna is part of the XL40 generation (2021-2026), sold as a minivan. Below: its service intervals with the source behind each one, the fluids it takes, and the NHTSA recalls issued for it.

Service schedule

What the 2021 Sienna needs, and when

All 11 of these items come from Toyota's own published schedule. Manufacturer rows link to Toyota's own schedule, Independent rows to a service shop or parts retailer's published guide.

ServiceIntervalSource
Engine oil and filter (A25A-FXS)

5,000 for severe duty

10,000 mi / 1 yearManufacturer
Engine air filter (A25A-FXS)30,000 mi / 3 yearsManufacturer
Cabin air filter (A25A-FXS)15,000 mi / 18 monthsManufacturer
Tire rotation (A25A-FXS)5,000 mi / 6 monthsManufacturer
Brake fluid (A25A-FXS)Inspect, replace as neededManufacturer
Engine coolant (A25A-FXS)100,000 mi / 10 yearsManufacturer
Transmission fluid (A25A-FXS)Inspect, replace as neededManufacturer
Spark plugs (A25A-FXS)120,000 mi / 12 yearsManufacturer
Serpentine belt (A25A-FXS)Inspect, replace as neededManufacturer
Differential and transfer case fluid (AWD)Inspect, replace as neededManufacturer
12V battery (A25A-FXS)Inspect, replace as neededManufacturer

Intervals are for normal driving; towing, short trips, extreme heat or dust shorten them. Services we could not find an interval for are left off rather than guessed.

Fluids and engines

What goes in it

Engine oil
0W-16, 4.8 qt
Coolant
SLLC
Transmission fluid
ATF WS

Powertrains in this generation

  • 2.5L 4-cyl hybrid (A25A-FXS), 245 hp, eCVT, FWD/AWD

Confirm the exact spec against the owner's manual or the label under the hood; capacities vary by engine and drivetrain.

Safety recalls

4 NHTSA recalls for the 2021 Toyota Sienna

From NHTSA's recall database, matched by model and year. Recall repairs are free at Toyota dealers, and a given car may already be fixed or fall outside a campaign, so check the VIN at nhtsa.gov/recalls before you buy.

Equipment adaptive/mobility

NHTSA 25V877000

December 2025

Vantage Mobility, LLC (VM) is recalling certain 2021-2026 Honda Odyssey, 2021-2025 Chrysler Pacifica, and Toyota Sienna vehicles equipped with QRT-Deluxe and QRT-Max wheelchair restraints. The retractors may not lock, preventing the wheelchair from being properly secured.

Remedy: Dealers will inspect and replace the retractors, free of charge. Owner notification letters was mailed January 27, 2026. Owners may contact Vantage Mobility customer service at 1-800-488-9082.

February 2025

Toyota Motor Engineering & Manufacturing (Toyota) is recalling certain 2021-2025 Sienna Hybrid vehicles. The bolts for the seatbacks on the third-row seat assemblies may not be tightened properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard (FMVSS) numbers 202, "Head Restraints," 207, "Seating Systems," and 225, "Child Restraint Anchorage Systems."

Remedy: Dealers will tighten the seat assembly bolts, free of charge. Owner notification letters were mailed April 1, 2025. Owners may contact Toyota's customer service at 1-800-331-4331. Toyota's number for this recall is 25TA05.

December 2023

Toyota Motor Engineering & Manufacturing (Toyota) is recalling certain 2020-2021 Avalon, Avalon Hybrid, Corolla, Highlander, Highlander Hybrid, RAV4, RAV4 Hybrid, Lexus ES350, Lexus RX350, Lexus RX450H, 2021 Sienna Hybrid, Lexus ES250, 2020-2022 Camry, Camry Hybrid, and ES300H vehicles. A short circuit may develop in the Occupant Classification System (OCS) sensor, preventing the front passenger air bag from deploying.

Remedy: Dealers will inspect and replace the sensor as necessary, free of charge. Interim letters notifying owners of the safety risk were mailed in February 2024. Some final remedy owner letters were mailed October 31, 2024. Letters will continue to be mailed in phases through January 2026. Owners may contact Toyota customer service at 1-800-331-4331. Toyota's number for this recall is 23TB15/23TA15 Lexus 23LB03/23LA03.

Electronic stability control (ESC)

NHTSA 22V239000

April 2022

Toyota Engineering & Manufacturing (Toyota) is recalling certain 2022 Lexus LX 600, Lexus NX 350h, Lexus NX 450h+, Toytoa RAV4 Hybrid, 2021-2022 Lexus LS 500h, Toyota Mirai, RAV4 PRIME, Sienna, Venza, and 2020-2022 Toyota Highlander Hybrid vehicles. The Skid Control ECU software may not turn on the Vehicle Stability Control (VSC) system when the vehicle is restarted after the driver has disabled the VSC system. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 126, "Electronic Stability Control Systems."

Remedy: Dealers will update the Skid Control ECU software, free of charge. Owner notification letters were mailed May 27, 2022. Owners may contact Toyota customer service at 1-800-331-4331. Toyota's number for this recall is 22TA03. Lexus' number for this recall is 22LA01.

Other Sienna model years

XL40 (2021-2026)

XL30 (2011-2020)

Shopping new? The Toyota Sienna guide covers the current model, with what it costs to keep for 1 to 15 years.

Sources

Researched 2026-09-16. Modeling, not mechanic advice - always confirm against your car's owner's manual and service records.

Running a Sienna for income?

Carlyle scores the exact listing on cost per remaining mile and projected Turo income, so you know what a 2021 Sienna earns before you buy it.

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